TABLE 2.
Organism (no. of strains) | Drug | No. of strains with MPC/MIC ratios of: |
|||||
---|---|---|---|---|---|---|---|
1 | 2 | 4 | 8 | 16 | >16 | ||
Acinetobacter baumannii (25) | Doripenem | 0 | 15 | 6 | 2 | 2 | 0 |
Imipenem | 0 | 11 | 9 | 1 | 4 | 0 | |
Meropenem | 0 | 8 | 12 | 1 | 4 | 0 | |
Pseudomonas aeruginosa (25) | Doripenem | 0 | 2 | 3 | 7 | 9 | 4 |
Imipenem | 0 | 1 | 5 | 7 | 9 | 3 | |
Meropenem | 0 | 0 | 4 | 7 | 6 | 8 | |
Escherichia coli (25) | Doripenem | 0 | 14 | 8 | 2 | 1 | 0 |
Ertapenem | 0 | 3 | 11 | 2 | 7 | 2 | |
Imipenem | 0 | 7 | 14 | 4 | 0 | 0 | |
Meropenem | 0 | 13 | 9 | 1 | 1 | 1 | |
Klebsiella pneumoniae (25) | Doripenem | 1 | 11 | 4 | 1 | 1 | 7 |
Ertapenem | 0 | 8 | 12 | 5 | 0 | 0 | |
Imipenem | 2 | 8 | 10 | 2 | 1 | 2 | |
Meropenem | 1 | 8 | 6 | 6 | 2 | 2 | |
Total strains (100) | Doripenem | 1 | 42 | 21 | 12 | 13 | 11 |
Ertapenema | 0 | 11 | 23 | 7 | 7 | 2 | |
Imipenem | 2 | 27 | 38 | 14 | 14 | 5 | |
Meropenem | 1 | 29 | 31 | 15 | 13 | 11 |
A. baumannii and P. aeruginosa were not included; a total of 50 strains were tested.