FIG. 5.

Antibacterial activity of D2S against P. aeruginosa Xen 5 in different body fluids was determined based on luminescence reading 3 h after addition of equal amounts of bacteria to equal volumes of PBS or PBS supplemented with 50% of human plasma, ascites, cerebrospinal fluid (CSF), saliva, or bronchoalveolar lavage (BAL) specimens. In each condition, the white column indicates the luminescent signal in control samples. Black and gray columns indicate the luminescent signal in the presence of 10 and 30 μM D2S, respectively. Data from one experiment performed in triplicate are shown. Two other experiments with samples obtained from different subjects show similar trends. *, significantly different from control sample.