FIG. 7.

D2S induced GFP-GR translocation from cytosol to nucleoplasm in BAECs. (A) GFP-GR nuclear localization. In this experiment BAECs were transfected with GFP-GR plasmid using Lipofectamine as a gene delivery strategy. (B) Quantitative evaluation of BAECs with nuclear localization of GFP-GR. After transfection, cells were grown for 24 h and treated with spermine (▵), dexamethasone (▴), dexamethasone-spermine (♦), disubstituted dexamethasone-spermine conjugate (□), and ceragenin CSA-13 (○). *, significantly different from control sample.