FIG. 4.

Box plots of the distributions of observed (Obs) and predicted (Pred) predose and postdose concentrations from 1,000 simulations from the final population model. The bold horizontal bars in the middle show the median values of vancomycin concentrations, while the outer boundaries of the boxes represent the ranges of the 25th and the 75th percentiles (interquartile ranges). The whiskers indicate the maximum and the minimum values of the concentrations. Outliers are not shown in these plots.