Skip to main content
. 2010 Apr 12;54(6):2626–2632. doi: 10.1128/AAC.01370-09

TABLE 2.

Variance changes related to the model-building processa

Model Covariate(s) ΔOFV BSVCL BSVV RUVσprop RUVσadd
Base None 0 43.6 30.5 36.3 1.41
1 Size on CL −157 30.3 28.9 32.6 1.57
2 PMA on CL −276 33.3 28.8 27.5 1.82
3 SCR on CL −227 36.9 29.4 27.4 2.09
4 PNA on CL −204 38.5 31.8 29.3 1.74
5 Ventilation on CL −56 40.9 31.2 35.9 1.67
6 SGA on CL 0 43.4 30.5 36.3 1.41
7 NSAID on CL 0 43.5 31.2 36.3 1.99
8 Race on CL −5 44.4 30.3 36.2 1.45
9 Size on V −12 45.3 6.4 31.8 2.32
10 Size and PMA on CL; size on V −449 23.3 12.0 23.0 1.52
12 Size, PMA, and race on CL; size on V −458 23.1 12.5 23.0 1.52
13 Size, PMA, and SCR on CL; size on V −426 23.1 10.8 22.9 2.18
Final Size, PMA, and SGA on CL; size on V −519 20.5 12.6 22.9 1.51
a

ΔOFV, change in objective function values; BSV, between-subject variability; RUVσprop, unexplained residual variability (proportional); RUVσadd, unexplained residual variability (additive); SCR, serum creatinine concentration.