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. 2010 Apr 5;54(6):2684–2686. doi: 10.1128/AAC.01545-09

TABLE 1.

Comparison of MICs of DC-159a with other quinolones and rifampin against M. tuberculosis

M. tuberculosis isolate type (n) Drug MIC (μg/ml)
Range 50% 90%
Drug susceptible (21) DC-159a 0.03-0.125 0.06 0.06
MXF 0.125-0.5 0.25 0.25
GAT 0.06-0.25 0.125 0.25
LVX 0.25-1 0.5 0.5
RIF ≤0.015-0.25 0.06 0.125
QR-MDR (11) DC-159a 0.125-0.5 0.125 0.5
MXF 1-4 2 4
GAT 0.5-2 1 2
LVX 2-16 8 16
RIF 16 to >128 128 >128