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. 2010 Mar 22;54(6):2401–2408. doi: 10.1128/AAC.01795-09

TABLE 1.

Sensitivities of WT and M230L RTs to NNRTIs

Polymerase and RT IC50 (nM)a
ETR DAP EFV NVP
DDDP
    WT 126 ± 28 131 ± 23 57 ± 7 3.2 × 103 ± 4 × 102
    M230L 1,320 ± 31 1,290 ± 32 910 ± 26 156 × 103 ± 8 × 102
        Fold change 10.5 9.9 16 48.8
RDDP
    WT 68 ± 9 19 ± 3 30 ± 6 4.1 × 103 ± 3 × 102
    M230L 696 ± 27 172 ± 31 740 ± 35 185 × 103 ± 13 × 103
        Fold change 10.2 9.1 24.7 45.1
a

Data represent the means ± standard deviations of three separate determinations.