TABLE 4.

Influence of growth and assay temperature on antibiotic susceptibilities of S. aureus

Growth temp (°C) and antibiotic	Avg MIC (μg/ml) at assay temp (°C) of:		P valuea
	15	37
37
Daptomycin	0.46 ± 0.07	1.5 ± 0.0	0.0021
Gentamicin	0.21 ± 0.04	0.34 ± 0.07	0.057
TMS	0.25 ± 0.0	1.33 ± 0.29b	0.002
15
Daptomycin	0.63 ± 0.21	1.5 ± 0.0	0.0021
Gentamicin	0.29 ± 0.08	0.38 ± 0.0	0.12
TMS	0.23 ± 0.03	0.42 ± 0.07b	0.013

^aP values shown are from a comparison of results of assays performed at 15°C versus 37°C.

^bMIC comparison of S. aureus strain COL grown at 37°C or 15°C and tested for susceptibility to TMS at 37°C, P = 0.006.