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In vitro antileishmanial activities of AIAs against intracellular L. donovani clinical isolates
| Compoundb | IC50 (μM)a vs L. donovani: |
||
|---|---|---|---|
| AG83-S | MC4-R | MC8-R | |
| DB745 | 0.13 ± 0.01 | 0.15 ± 0.02 | 0.16 ± 0.03 |
| DB766 | 0.090 ± 0.013 | 0.076 ± 0.005 | 0.064 ± 0.010 |
| Sb(V) | 9.0 ± 0.5 | 44 ± 3 | 40 ± 5 |
| Sb(III) | 6.2 ± 1.8 | 32 ± 5 | 26 ± 5 |
Mean ± standard deviation of at least three independent determinations.
Sb(V), sodium stibogluconate; Sb(III), sodium antimony tartrate.
