TABLE 2.

Quantification of BrdU-positive cells in the distal colon sections of WT and NOX1^KO mice^a

Time	No. of BrdU-positive cells/crypt in:		Relative decrease (%)
	Wild-type mice	NOX1KO mice
1 h	11.45 ± 2.15	7.83 ± 1.80*	∼30
24 h	25.86 ± 5.30	24.12 ± 4.65	∼7

^aOne hundred independent glands of 6 independent WT and NOX1^KO mice were counted. Numbers of BrdU-positive cells per gland section after 1 h of BrdU correspond to poliferating crypt progenitor cells. After 24 h of BrdU, the leading edge of BrdU labeling marks the furthest extent of migration of progeny of precursor cells that have divided. *, P < 0.01 relative to control by Student's t test.