FIG. 3.

Consumptive coagulopathy was not present during the disease course. The APTT (A and B), which are not dependent on platelet counts, were steady or modestly prolonged several days after Stx1 or Stx2 challenge. Fibrinogen levels (C and D) are shown as a percentage of the T0 value for each animal. The absolute fibrinogen level at T0 before challenge was 141.8 ± 40.6 mg/dl (n = 21). The symbols for toxin doses are the same as those in Fig. 2. Data shown are means ± SD.