TABLE 2.

Distribution of the ureA, ureB, ureI, ggt, gltS, dcuA, and ans genes in Helicobacter species for which complete genome sequences are available

Helicobacter strain	Host	Presence (+) or absence (−) of indicated gene
		ureA	ureB	ureI	ggt	gltS	dcuA	ans (SP)a	ans (no SP)a
Gastric
H. pylori 26695	Human	+	+	+	+	+	+	+	−
H. pylori 98-10	Human	+	+	+	+	+	+	+	−
H. pylori B128	Human	+	+	+	+	+	+	+	−
H. pylori G27	Human	+	+	+	+	+	+	+	−
H. pylori HPAG1	Human	+	+	+	+	+	+	+	−
H. pylori HPKX_438_AG0C1	Human	+	+	+	+	+	+	+	−
H. pylori HPKX_438_CA4C1	Human	+	+	+	+	+	+	+	−
H. pylori J99	Human	+	+	+	+	+	+	+	−
H. pylori P12	Human	+	+	+	+	+	+	+	−
H. pylori Shi470	Human	+	+	+	+	+	+	+	−
H. acinonychis Sheeba	Wildcat	+	+	+	+	+	+	+	−
H. mustelae ATCC 43772	Ferret	+	+	+	+	+	−	−	+
Enterohepatic
H. canadensis MIT 98-5491	Human	−	−	−	−	+	+	−	+
H. cinaedi CCUG 18818	Hamster	−	−	−	−	−	+	−	+
H. pullorum MIT 98-5489	Bird	−	−	−	−	+	+	+	−
H. winghamensis ATCC BAA-430	Human	−	−	−	−	+	+	+	−
H. bilis ATCC 43879	Human, mouse, and dog	+	+	+	+	+	+	+	−
H. hepaticus ATCC 51449	Mouse	+	+	+	−	−	+	+	−

^aans, gene encoding asparaginase. No assignment to either ansA or ansB genes encoding closely related asparaginases was done, since our phylogenetic analysis (see tree shown in Fig. S4 in the supplemental material) revealed several inconsistencies with the previous annotations. SP, a signal peptide was detected on the sequence (SignalP 3.0 hidden Markov model [HMM] score ≥ 0.750); no SP, a signal peptide was not detected (SignalP 3.0 HMM score < 0.750).