FIG. 8.

Difference in the phagocytosis of L. monocytogenes (LM) and bacterial burden between WT and TLR2^−/− mice after L. monocytogenes infection in vivo. (A) WT, TLR2^−/−, and MyD88^−/− mice were injected i.p. with 3 ml of 3% thioglycolate medium and infected i.p. with 1 × 10⁸ CFU of L. monocytogenes 4 days later. Five minutes after infection, PECs were collected, and the number of phagocytosed L. monocytogenes was determined. *, P < 0.05. (B) WT and TLR2^−/− mice were infected intravenously with 10⁴ CFU of L. monocytogenes. The spleens were removed 1 day after infection, and the number of viable bacteria in spleen was determined. *, P < 0.05.