FIG. 2.

Kinetics of in vivo gene expression following pulmonary DNA immunization. Mice were immunized with 20 μg of luciferase DNA or plasmid DNA expressing the HIV-1 HXB2 gp120 protein either in solution or complexed to PEI. (A) Representative IVIS images of luciferase expression in a mouse immunized with luciferase DNA. (B) Log relative light units (RLU) expressed by groups of six to eight mice ± SE. (C) Kinetics of p18-specific CD8⁺ T-cell responses in the peripheral blood of HIV-1 HXB2 gp120 immunized mice. Data represent means from six to eight mice ± SE.