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. 2010 Mar 24;84(11):5508–5519. doi: 10.1128/JVI.02483-09

FIG. 4.

FIG. 4.

Frequency of mutations in 3 HLA-A*1101-restricted epitopes. Three epitope sequences, Gag349 (A), Nef73 (B), and Nef84 (C), from HLA-A*1101-positive and HLA-A*1101-negative individuals chronically infected with HIV-1 were analyzed. Consensus sequences of these epitopes in clade B are as follow: Gag349, ACQGVGGPGHK; Nef73, QVPLRPMTYK; Nef84, AVDLSHFLK and ALDLSHFLK. The frequency of mutations in the total sequence of the epitopes was calculated as (number of individuals having the mutation[s]/number of individuals tested) × 100, whereas those at a given position were calculated as (number of individuals having the mutation[s] at a given position/number of individuals tested) × 100. The results were compared between HLA-A*1101-positive and HLA-A*1101-negative individuals, and the P values were determined by using Fisher's exact test.