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Total breadth of IFN-γ-positive Gag-specific CD8 T cells (mean, 2.45 ± 2.35) in a cohort of 288 HIV-1 clade C-infected Zulu/Xhosa, as measured by ELISPOT assay with overlapping peptides (n = 410) to all expressed proteins. Subjects were selected from the upper box (dotted line), representing high Gag responders, and the lower box (dashed line), representing low Gag responders, based on sample availability.
