Figure 6. Monomeric proton channels (mVSOPΔNΔC or H_V1ΔC) are less sensitive to the slowing effect of Zn²⁺ than WT dimeric channels (mVSOP or H_V1).

Plotted is the mean ±s.e.m. residual slowing after correction for the observed shift of the g_H–V relationship in each cell at each [Zn²⁺]. Slowing is defined as the ratio τ_act(Zn²⁺)/τ_act, which was determined at moderate depolarizations in the voltage range where τ_act is approximately exponentially dependent on voltage. For mVSOPΔNΔC and mVSOP, n= 3–4; for H_V1 and H_V1ΔC, n= 8–11. *P < 0.05 for truncated vs. WT channels.