Table 1.
Measurement | Double mutant | Control | P value |
---|---|---|---|
Weight (females) | 11±2.6 g, n=2 | 23±2.1 g, n=6 | <0.0001 |
Weight (males) | 10±2.4 g, n=11 | 30±3.6 g, n=11 | <0.0001 |
Body temperature | 35±1.1 °C, n=10 | 37±0.3 °C, n=20 | <0.0001 |
Non-fasting blood glucose | 50±14 mg/dL, n=2 | 143±13 mg/dL, n=7 | <0.0001 |
Fasting blood glucose | 26±2.8 mg/dL, n=2 | 78±12 mg/dL, n=10 | =0.0002 |
Resting serum lactate | 5.7±1.7 mmol/L, n=7 | 3.9±1.2 mmol/L, n=9 | =0.02 |
Post-exercise lactate | 9.5±2.3 mmol/L, n=5 | 4.7±0.65 mmol/L, n=5 | =0.002 |
Measurements are given as value±standard deviation. P values were calculated using the unpaired-t test. Controls are mixed genotype littermates of double mutant animals. The number of animals (n) for each measurement is indicated.