Table 2.
L/R brain region | Z-score | Coordinates (x, y, z) | Cluster size |
---|---|---|---|
MTL-VISUAL IC | |||
Frontal cortex | |||
L middle frontal gyrus (BA 8/9/6) | 6.65 | −26, 30, 41 | 121 |
L anterior cingulate (BA 24) | 5.34 | −8, 19, 23 | 37 |
L inferior frontal gyrus (BA 9) | 5.30 | −41, 8, 30 | 57 |
Bilateral anterior cingulate (BA 32) | 4.66 | 4, 41, 0 | 34 |
R middle frontal gyrus (BA 8) | 4.27 | 26, 30, 41 | 14 |
R middle frontal gyrus (BA 46/9) | 3.85 | 41, 23, 23 | 31 |
Temporal lobes and posterior regions | |||
Bilateral lingual gyrus, cuneus, precuneus, R posterior middle temporal gyrus, R middle temporal gyrus, R hippocampus, R amygdala (BA 19/7/39/21) | 13.79 | 19, −68, −4 | 3221 |
R precuneus (BA 7) | 7.60 | 4, −45, 53 | 463 |
L inferior parietal lobe (BA 40) | 4.97 | −53, −34, 41 | 15 |
L middle/inferior temporal gyri (BA 21/20) | 4.87 | −60, −23, −4 | 94 |
L parahippocampal gyrus/amygdala | 4.77 | −23, −8, −11 | 14 |
L superior temporal gyrus (BA 38) | 4.66 | −38, 8, −26 | 23 |
R angular gyrus (BA 39) | 4.43 | 34, −56, 38 | 25 |
Mid brain | |||
L thalamus | 6.70 | −4, −11, 0 | 48 |
DEFAULT NETWORK IC2 | |||
Frontal cortex | |||
Medial PFC, anterior cingulate gyrus, L inferior frontal gyrus, L superior temporal gyrus (BA 10/9/8/6/24/47/38) | 16.39 | 0, 60, 23 | 3879 |
R superior temporal, inferior frontal gyri (BA 38/47) | 8.09 | 34, 19, −23 | 202 |
R postcentral, precentral gyri (BA 3/6) | 7.59 | 41, −23, 53 | 168 |
L precentral gyrus (BA 4) | 5.82 | −38, −23, 56 | 53 |
Temporal lobes and posterior regions | |||
Bilateral cingulate and posterior cingulate gyri, precuneus (BA 24/31/7) | 12.45 | 0, −60, 26 | 465 |
R middle, superior, inferior temporal gyri (BA 21/22/20) | 9.76 | 60, −23, −15 | 399 |
R lingual gyrus, cuneus (BA 18/17) | 7.13 | 4, −83, −8 | 89 |
R parahippocampal gyrus/hippocampus (BA 27) | 5.94 | 23, −30, −8 | 71 |
L hippocampus | 4.46 | −11, −38, 4 | 6 |
L hippocampus | 3.86 | −23, −15, −19 | 8 |
Mid brain | |||
L thalamus | 6.04 | −11, −34, 4 | 27 |
R striatum (caudate) | 3.77 | 11, 4, 11 | 12 |
One component included medial temporal and ventral visual areas associated with memory, emotion, and complex visual perception (MTL-visual; see Figure 1) while the second component included brain regions involved in self-referential/default mode processing, social cognition, and memory (default network IC2; see Figure 1). Coordinates are in Montreal Neurological Institute stereotaxic space.
BA, Brodmann area; L, left hemisphere; PFC, prefrontal cortex; R, right hemisphere.