Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Mar 23;19(12):2421–2432. doi: 10.1093/hmg/ddq125

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2010. Published by Oxford University Press

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — NHS is essential for organization of the circumferential actin ring. (A) Knockdown of NHS in Caco-2 cells resulted in larger cells, loss of a cuboidal cell shape and a diffuse localization of α-catenin (green) at the cell periphery. Scale bar 10 µm. Nuclei stained with DAPI (blue). (B) NHS siRNA treatment resulted in a 2.5-fold increase in cell area. For each condition, 100 cells from two independent experiments were measured. Error bars are ±standard deviation. (C) The thick circumferential ring of actin bundles (counterstained for F-actin, green) aligned with the cell borders was disrupted in NHS-depleted cells. Nuclei stained with DAPI (blue). Scale bar 10 µm.