Table 1.
Demographic details of subjects included in the study, stratified by diagnosis and by genotype
Ser704Cys (rs826161) | |||
Genotype | Ser704/Ser704 (n = 72) | Ser704/Cys704 (n = 65) | Cys704/Cys704 (n = 11) |
Age (years) | 48 ± 15 | 44 ± 16 | 46 ± 15 |
Post mortem delay (h) | 37 ± 16 | 35 ± 19 | 29 ± 17 |
Brain pH | 6.5 ± 0.3 | 6.5 ± 0.3 | 6.4 ± 0.2 |
Sex (male:female) | 49:23 | 39:26 | 7:4 |
Racea | 34AA, 29C, 6H, 3A | 43AA, 21C | 7AA, 3C, 1H |
Leu607Phe (rs6675281) | |||
Genotype | Leu607/Leu607 (n = 102) | Leu607/Phe607 (n = 41) | Phe607/Phe607 (n = 5) |
Age (years) | 47 ± 16 | 46 ± 15 | 45 ± 20 |
Post mortem delay (h) | 34 ± 17 | 41 ± 17 | 27 ± 18 |
Brain pH | 6.5 ± 0.3 | 6.4 ± 0.3 | 6.4 ± 0.4 |
Sex (male:female) | 68:34 | 22:19 | 5:0 |
Race | 50AA, 41C, 7H, 3A | 29AA, 12C | 5AA |
Diagnosis | Control (n = 81) | Schizophrenia (n = 67) | |
Age (years) | 42 ± 15 | 52 ± 16 | |
Post mortem delay (h) | 32 ± 15 | 40 ± 19 | |
Brain pH | 6.6 ± 0.3 | 6.4 ± 0.3 | |
Sex (male:female) | 54:27 | 41:26 | |
Race | 46AA, 28C, 4H, 3A | 38AA, 25C, 3H | |
Age at onset (years) | — | 23 ± 8 |
Values are mean ± standard deviation.
A, Asian Pacific; AA, African American; C, Caucasian; H, Hispanic.
aRace was unknown for one subject.