Table 4.
Coefficients for the main effect variables* in the APACHE IV multivariable regression model that predicts remaining intensive care unit (ICU) stay after day 5.
| Variable | Coefficient | p-value |
|---|---|---|
| DAY 1 | ||
| APS (per 10 units) | -0.37470 | 0.02 |
| AIDS | 0.76707 | 0.30 |
| Cirrhosis | -0.69324 | 0.10 |
| Hepatic Failure | -1.00013 | 0.02 |
| Immunosuppression | -0.16578 | 0.41 |
| Lymphoma | -0.79370 | 0.18 |
| Leukemia or Myeloma | -1.22184 | 0.02 |
| Metastatic Tumor | 0.04277 | 0.89 |
| Admitted from the Floor | 0.02120 | 0.91 |
| Admitted from the Operating/Recovery Room | -0.37637 | 0.63 |
| Admitted from Other Hospital | -0.27897 | 0.27 |
| Length of Stay before ICU Admission (per day) | -0.43308 | 0.22 |
| Age (per 10 years) | -0.11960 | 0.41 |
| (PaO2 : FiO2 )/10 on Day 1 (per 10 units) | -0.00285 | 0.99 |
| Emergency Surgery? | -0.37896 | 0.26 |
| Ventilated on Day 1? | -1.59366 | <0.01 |
| Unable to Assess Glasgow Coma Score on Day 1? | -2.43030 | <0.01 |
| Rescaled Glasgow Coma Score on Day 1 | -0.09905 | <0.01 |
| Day 1 ICU Length of Stay Prediction (per day) | 0.84742 | <0.01 |
| Readmission to ICU? | 0.18283 | 0.44 |
| DIAGNOSTIC CATEGORIES (non-operative) | ||
| Airway obstruction | -0.36374 | 0.67 |
| Aspiration pneumonia | -0.02422 | 0.96 |
| Bacterial pneumonia | -0.60479 | 0.16 |
| Cardiac arrest | -0.01874 | 0.97 |
| Cardiogenic shock | 0.91314 | 0.19 |
| Congenstive heart failure | 0.21795 | 0.63 |
| Hyperglycemic hyperosmolar-nonketotic coma | -0.46909 | 0.52 |
| COPD (emphysema/bronchitis) | -0.11881 | 0.81 |
| Cardiovascular, other | 0.72263 | 0.14 |
| General, other | 0.75895 | 0.19 |
| GI bleeding, upper | -0.42147 | 0.34 |
| GI, other | 0.25619 | 0.64 |
| Hepatic failure | -2.31722 | <0.01 |
| Hypovolemia/dehydration (not shock) | 0.07455 | 0.92 |
| Intracerebral hemorrhage | 0.97105 | 0.04 |
| Multiple trauma (excluding head trauma) | 0.85690 | 0.10 |
| Neurologic, other | 0.46786 | 0.42 |
| Drug overdose | -0.15812 | 0.80 |
| Pancreatitis | 0.06019 | 0.94 |
| Pleural effusion | 0.71845 | 0.37 |
| Pulmonary edema (noncardiac, ARDS) | -1.15959 | 0.03 |
| Pulmonary embolism | -0.35920 | 0.62 |
| Renal, other | 0.43602 | 0.49 |
| Respiratory arrest | 0.89615 | 0.07 |
| Respiratory, other | 0.47893 | 0.26 |
| Rhythm disturbance | 0.67577 | 0.26 |
| Subarachnoid hemorrhage, intracranial aneurysm | 1.46182 | 0.01 |
| Subdural/epidural hematoma | -0.71143 | 0.31 |
| Seizure (no structural disease) | -0.50347 | .50 |
| Sepsis, gastrointestinal | -0.25015 | 0.66 |
| Sepsis, other location | -0.36255 | 0.53 |
| Sepsis, pulmonary | -0.06425 | 0.90 |
| Sepsis, unknown location | -0.49536 | 0.36 |
| Sespsis, urinary tract | 0.33721 | 0.56 |
| Sepsis, cutaneous | -0.5287 | 0.51 |
| Stroke | -0.59321 | 0.27 |
| Head trauma with multiple other injuries | -0.55691 | 0.45 |
| Head trauma only | 1.79925 | <0.01 |
| DIAGNOSTIC CATEGORIES (post-operative) | ||
| Aortic aneurysm, elective repair | 1.06657 | 0.24 |
| GI malignancy | 2.07196 | 0.04 |
| CABG with single valve surgery | 4.09432 | <0.01 |
| Craniotomy or transsphenoidal procedure, neoplasm | 1.56513 | 0.14 |
| Cardiovascular surgery, other | 3.95827 | <0.01 |
| GI obstruction | 0.79922 | 0.42 |
| GI surgery, other | 2.59499 | <0.01 |
| GI, perforation | 1.47170 | .12 |
| GI, vascular ischemia | 0.96945 | 0.35 |
| Multiple trauma including the head | -0.41853 | 0.73 |
| Multiple trauma excluding the head | 1.88865 | 0.05 |
| Neurologic surgery, other | 2.64227 | <0.01 |
| Peripheral ischemia (embolectomy, thrombectomy, dilation) | 1.95534 | 0.07 |
| Respiratory surgery, other | 2.24947 | 0.01 |
| Thoracotomy, malignancy | 2.98145 | <0.01 |
| Aortic aneurysm, rupture | -0.22531 | 0.84 |
| Subarachnoid hemorrhage (aneurysm, arteriovenous malformation) | 2.16347 | 0.06 |
| Subdural/epidural hemtoma | 0.67618 | 0.54 |
| Head trauma only | -0.00303 | 0.99 |
| Valvular heart surgery | 3.21080 | <0.01 |
| DAY 5 | ||
| APS taken on Day 5 (per 10 units) | 0.75210 | <0.01 |
| Ventilated on Day 5? | 2.22229 | <0.01 |
| Unable to Assess Glasgow Coma Score on Day 5? | 3.94695 | <0.01 |
| (PaO2 : FiO2 )/10 on Day 5 (per 10 units) | -0.96110 | <0.01 |
| Rescaled Glasgow Coma Score on Day 5 | 0.19615 | <0.01 |
| Delta APS Day 4 - APS Day 5 (per 10 units) | 0.11160 | <0.01 |
No selection methodology was used.
*All variables except for the spline terms
APS = Acute physiology score of APACHE III; AIDS = Acquired immunodeficiency syndrome; GI = Gastrointestinal; ARDS = Adult respiratory distress syndrome; CABG; Coronary artery bypass graft;