Table II.
Allele and genotype frequencies and p-values from allelic and genotypic associations. Minor allele frequencies in cases and controls (MAF), genotype frequencies (Geno. Freq) and P-values for allelic association from Fisher's Exact test and genotypic association from logistic regression using the additive genetic model are shown for the Washington University (WU), MRC and Alzheimer's disease Neuroimaging Initiative (ADNI) series.
SNP | MAF | Allelic p-value | Geno Freq | Geno p-value | |
---|---|---|---|---|---|
WU | rs1049296 | 0.15 | 0.14 | 0.02/0.27/0.71 | 0.13 |
rs1800562 | 0.04 | 0.89 | <0.01/0.08/0.92 | 0.89 | |
MRC | rs1049296 | 0.15 | 0.72 | 0.03/0.25/0.72 | 0.72 |
rs1800562 | 0.02 | 0.58 | <0.01/0.03/0.97 | 59 | |
ADNI | rs1049296 | 0.15 | 0.61 | 0.03/0.25/0.72 | 0.61 |
rs1800562 | 0.01 | 0.77 | <0.01/0.02/0.98 | 0.72 | |
COMB | rs1049296 | 0.15 | 0.46 | 0.02/0.25/0.72 | 0.46 |
rs1800562 | 0.02 | 0.46 | <0.01/0.04/0.90 | 0.45 |