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. Author manuscript; available in PMC: 2010 May 27.
Published in final edited form as: Transfusion. 2004 Feb;44(2):164–169. doi: 10.1111/j.1537-2995.2004.00615.x

TABLE 1.

Expected band sizes (bp) for Knops genotyping with PCR-RFLP*

Polymorphism Base pair change Amino acid change Enzyme Homozygous wild type Heterozygous Homozygous mutant
Kna/Knb 4708G>A V1561M NdeI 305 305, 261, 44 261, 44
McCa/McCb 4795A>G K1590E BsmI 305 305, 166, 139 166, 139
Sl1/Sl2 4828A>G R1601G MfeI 305 305, 161, 144 161, 144
*

Mutant alleles (Knb, McCb, Sl2) were cut by the restriction enzyme indicated.