Table 1.
Frequency of stressful events and instantaneous passage of gavage needle in mice
| Water-coated gavage needles |
Sucrose-coated gavage needles |
|||
| Trial | No. of stressful events (%) | No. of instantaneous passages (%) | No. of stressful events (%) | No. of instantaneous passages (%) |
| 1 | 13 of 18 (72.2) | 0 of 18 (0) | 5 of 18 (27.7) | 1 of 18 (5.6) |
| 2 | 7 of 17 (41.1) | 0 of 17 (0) | 6 of 19 (31.6) | 3 of 19 (15.8) |
| 3 | 6 of 20 (30.0) | 0 of 20 (0) | 2 of 16 (12.5) | 4 of 16 (25.0) |
| 4 | 6 of 17 (35.3) | 0 of 17 (0) | 1 of 19 (5.3) | 4 of 19 (21.1) |
| 5 | 4 of 18 (22.2) | 0 of 18 (0) | 1 of 18 (5.6) | 4 of 18 (22.2) |
| 6 | 2 of 17 (11.8) | 2 of 17 (11.8) | 1 of 19 (5.3) | 8 of 19 (42.1) |
| 7 | 2 of 16 (12.5) | 0 of 16 (0) | 1 of 20 (5.0) | 10 of 20 (50.0) |
| Total | 40 stressful events 84 nonstressful events | 2 instantaneous passages 122 non-instantaneous passages | 17 stressful events 111 nonstressful eventsa | 34 instantaneous passages 94 non-instantaneous passagesb |
a
Number of stressful events significantly fewer (P < 0.01, χ2 analysis) compared with value for water-coated gavage needles.
b
Number of instantaneous gavage passages significantly increased (P < 0.01, χ2 analysis) compared with value for water-coated gavage needles.