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Example for tug-of-war. (a) A cargo with a total number of N+ = 4 (solid) plus and N− = 3 (open) minus motors is pulled by a fluctuating number of motors. Only three of the (N+ +1)(N− +1) = 20 possible configurations of (n+, n−) are shown. (b) The trajectory of a cargo transported by four kinesin and three dynein motors with parameters as in Table S1 exhibits stochastic switching between fast plus and fast minus motion.
