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Off-resonance spin-locking geometry. The effective field ωeff makes an angle φ = tan−1(ω1/Δω) with the z-axis. To perform off-resonance spin locking, the magnetization must be flipped parallel to the effective field such that the flip angle α = ϕ; however, B1 imperfections cause deviations in the expected flip angle α = ϕ − Δϕ. In on-resonance spin-locking experiments, ωeff = ω1 and ϕ = 90°.
