Table 2.
Baseline demographics and background characteristics of patients*
| N = 213 | |
|---|---|
| Sex n (%) | |
| Male | 104 (48.8) |
| Female | 109 (51.2) |
| Race n (%) | |
| African | 213 (100) |
| Mean age (yr) | 3.2 |
| SD | 1.5 |
| Range | 0.7–7.9 |
| Mean weight (kg) | 14.2 |
| SD | 2.8 |
| Range | 10–20 |
| Age categories n (%) | |
| < 1.5 years | 27 (12.7) |
| ≥ 1.5 to < 3.5 years | 104 (48.8) |
| ≥ 3.5 to < 5 years | 51 (23.9) |
| ≥ 5 years | 31 (14.6) |
| Mean height (cm) | N = 212 94.8 |
| SD | 11.5 |
| Range | 72–123 |
| Mean parasite density, asexual forms (/µL) | 36,476 |
| SD | 43,593 |
| Range | 1,000–248,800 |
*
For modified safety population (i.e., all patients who took at least one dose of study medication and had a post-baseline neuropsychiatric assessment on Day 7 or who reported a drug-related neuropsychiatric adverse event at any time before a new malaria episode occurred).