Table 4.
Kaplan Meier estimate | 95% CI | |
---|---|---|
ACPR-PCR corrected (%) | ||
Day 28 | 96.6 | 93.0 to 98.4 |
Day 63 | 96.6 | 93.0 to 98.4 |
ACPR-uncorrected (%) | ||
Day 28 | 96.1 | 92.4 to 98.0 |
Day 63 | 85.4 | 79.7 to 89.7 |
For modified intention-to-treat population (i.e., all patients who had positive parasitemia at baseline and took at least one dose of study medication; patients who discontinued the study before Day 4 without previous occurrence of early treatment failure or who had a mixed strain infection were excluded).
ACPR = adequate clinical and parasitological response; CI = confidence interval; PCR corrected = polymerase chain reaction method was used to exclude new P. falciparum infections from this analysis.