Figure 3.

The 5′-nucleotidase/apyrase family of black flies, mosquitoes, tabanids compared with Drosophila and mammalian enzymes. The Simulium nigrimanum proteins are Sim-214 and Sim187. The remaining sequences are named with the first three letters from the genus name followed by two letters from the species name and by their National Center for Biotechnology Information (NCBI) protein accession number. The box shows the deletion of the membrane anchor region in the salivary apyrases of Diptera. The symbols above the alignment indicate: (*) identical sites; (:) conserved sites; (.) less conserved sites. This figure appears in color at www.ajtmh.org.