Table 2.
Microarray and real time PCR data of differential gene expression of genes in brains of T. b. brucei infected mice*
| Molecule | Fold changes in gene expression | |||
|---|---|---|---|---|
| Microarray | Real time PCR | |||
| 6 vs. 28 d.p.i. | 15 vs. 28 d.p.i. | 6 vs. 28 d.p.i. | ||
| Biglycan | 6.16 | 4.23 | 1.71 | |
| BCKDHA | 4.50 | 4.46 | NDE | |
| Carbonic anhydrase 9 | 2.13 | 2.11 | NDE | |
| Ceruloplasmin | 3.49 | 2.25 | 3.03 | |
| Cystatin C | 3.80 | 2.10 | 1.5 | |
| CRP61 | 2.65 | 2.40 | NDE | |
| Eph receptor A4 | 1.52 | 2.12 | NDE | |
| GFAP | 2.49 | 2.66 | 3.18 | |
| Granulin | 2.63 | 2.36 | 4.99 | |
| IP-30 | 4.15 | 2.92 | 7.43 | |
| LRRC4 | 1.57 | 1.84 | NDE | |
| Lipocalin 2 | 1.80 | 1.96 | 15.50 | |
| Midkine | 2.13 | 1.54 | 1.83 | |
| Neuronal pentraxin 1 | 1.56 | 2.00 | NDE | |
| Prominin 1 | 2.09 | 2.08 | 2.33 | |
| Reelin | 1.42 | 1.63 | 4.01 | |
| SLPI | 2.54 | 1.72 | 84.78 | |
| Serglycin | 1.98 | 2.80 | 5.94 | |
| Serpina3n | 3.30 | 3.37 | 3.96 | |
| Spon1 | 1.90 | 1.70 | 1.433 | |
| ST6GALNAC5 | 1.82 | 2.06 | NDE | |
| Syndecan 4 | 2.18 | 1.55 | 1.69 | |
| Translocator protein | 3.63 | 2.17 | 5.00 | |
| Vimentin | 4.26 | 3.57 | NDE | |
BCKDHA = branched chain ketoacid dehydrogenase E1, alpha polypeptide; CRP61 = cysteine-rich protein 61; GFAP = glial fibrillary acidic protein IP-30 - Interferon gamma inducible protein 30; LRRTM4 = leucine-rich repeat containing 4; SLPI = secretory leukocyte peptidase inhibitor; Serpina3n = serine (or cysteine) peptidase inhibitor, clade A, member 3N; Spon1 = spondin 1, (f-spondin) extracellular matrix protein; ST6GALNAC5 = ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; NDE = no differential expression.