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. 2010 Mar 26;171(8):859–867. doi: 10.1093/aje/kwq028

Table 6.

Geometric Mean Levels of Proinflammatory Cytokines in Small- and Appropriate-for-Gestational-Age Preterm Births (n = 62)a, by Reason for Preterm Delivery, Infant Growth Project, Jefferson County, Alabama, 1985–1988

Small-For-Gestational-Age Birth
Appropriate-For-Gestational-Age Birth
P Valueb
No. GM, pg/mL 95% CI No. GM, pg/mL 95% CI
Interleukin-12
    Spontaneous/PROM preterm birth 8 3.3 2.4, 4.8 49 4.5 3.9, 5.3 0.06
    Indicated preterm birth 2 3.7 1.2, 11.6 3 5.9 2.2, 11.1 0.34
Interferon γ
    Spontaneous/PROM preterm birth 8 3.3 2.1, 5.2 49 8.4 6.4, 11.0 <0.01
    Indicated preterm birth 2 6.2 0.6, 60.3 3 9.9 2.2, 44.3 0.36
Tumor necrosis factor α
    Spontaneous/PROM preterm birth 8 7.9 6.9, 9.2 49 10.9 9.7, 12.3 0.02
    Indicated preterm birth 2 12.6 11.4, 13.9 3 12.3 11.2, 13.4 0.64

Abbreviations: CI, confidence interval; GM, geometric mean; PROM, premature rupture of the membranes.

a

There were 72 preterm births in the study population. However, for 10 of these births, information on the type of preterm delivery was missing. There was 1 large-for-gestational-age preterm baby, who was grouped with appropriate-for-gestational-age births.

b

P value was calculated using Fisher's exact test.