Table V.
HSV-2 peptides recognized by IS subjects
| Subject |
ORF |
Peptide |
Sequence |
CD4/CD8 |
|---|---|---|---|---|
| IS2 | gD-2 | gD-2245-259 | LPRFIPENQRTVALY | CD4 |
| |
gD-2 |
gD-2272-286 |
YTSTLLPPELSDTTN |
CD4 |
| IS4 | ICP4 | ICP41001-1015 | GLSCLLAALGNRLCG | CD8 |
| ICP4 | ICP41009-1023a | LGNRLCGPATAAWAG | CD8 | |
| ICP4 | ICP41109-1123 | ARDLRRTVLASGRVF | CD8 | |
| ICP4 | ICP41161-1175 | FGPDTLVPMSPREYR | CD8 | |
| |
ICP4 |
ICP41169-1183 |
MSPREYRRAVLPALD |
CD8 |
| IS5 | UL27 (gB-2) | gB-2141-155 | IAVVFKENIAPYKFK | ndb |
| |
ICP4 |
ICP41009-1023 |
LGNRLCGPATAAWAG |
CD8 |
| IS6 | UL49 | UL4945-59 | PMRARPRGEVRFLHY | CD8 |
| |
UL29 |
UL29993-1007 |
GNDRVFQAGNWASLL |
nd |
| IS7 | ICP0 | ICP0156-170 | IPLRNTCPLCNTPVA | nd |
| ICP0 | ICP0636-650 | SASGAGERRETSLGP | nd | |
| |
ICP0 |
ICP0648-662 |
LGPRAAAPRGPRKCA |
nd |
| IS9 | ICP0 | ICP0636-650 | SASGAGERRETSLGP | nd |
| ICP0 | ICP0648-662 | LGPRAAAPRGPRKCA | nd | |
| UL39 | UL39309-323 | PTVGTDPGYPVPLEL | nd | |
| UL39 | UL391093-1107 | TLPASTLVRLLVHAY | nd | |
| |
ICP4 |
ICP4777-791 |
FQNQSLRPLLADTVA |
nd |
| IS10 | ICP0 | ICP0636-650 | SASGAGERRETSLGP | nd |
| ICP0 | ICP0648-662 | LGPRAAAPRGPRKCA | nd | |
| UL29 | UL2989-103 | HYSPSVYVFHGGRHL | nd | |
| |
UL29 |
UL2993-107 |
SVYVFHGGRHLAPST |
nd |
| IS11 |
UL19 |
UL19785-800 |
HNTQARAADAADDRPH |
CD8 |
| IS12 | ICP22 | ICP2217-31 | NHAPPSPPPGSRKRR | nd |
| |
UL39 |
UL39109-123 |
TAVVALGGTSGPSAT |
nd |
| IS13 |
ICP4 |
ICP4777-791 |
FQNQSLRPLLADTVA |
nd |
| IS19 | UL39 | UL3917-31 | SERQEPREPEVAPPG | nd |
| UL39 | UL3925-39 | PEVAPPGGDHVFCRK | nd | |
| UL39 | UL39309-317 | PTVGTDPGY | CD8 | |
| UL39 | UL39313-327 | TDPGYPVPLELTPEN | nd | |
| ICP0 | ICP05-23 | PGTSSRADPGPERPPRQTP | nd | |
| ICP0 | ICP017-30 | RPPRQTPGTQPAAPH | nd | |
| ICP0 | ICP0123-142 | VCAVCTDEIAPPLRCQSFP | nd | |
| ICP0 | ICP0135-149 | LRCQSFPCLHPFCIP | nd |
a
Shaded cells indicate epitopes recognized in more than 1 IS subject.
b
nd: not determined due to lack of PBMC or response below level of detection of ICS assay.