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. 2009 Sep 30;27(2):297–310. doi: 10.1093/molbev/msp233

Table 1.

Summary of Simulations Performed.

Model Violation # Simulations (39 Total) Parameter, Simulated Values Further Details
IM model (baseline – no violations), IS evolution 1 NA IS simulation using MS; IS model specified in IMA
IM model, HKY evolution 1 NA HKY simulation using SEQ-GEN based on trees simulated in MS; HKY model specified in IMA
IM model, IS evolution, HKY substitution model 1 NA Same data sets, priors, and starting seeds as baseline IS runs, but with HKY model specified in IMA
IM model, HKY evolution, IS substitution model 1 NA HKY simulation using SEQ-GEN based on trees simulated in MS; analyzed largest sequence blocks with no four-gamete test violations; IS model specified in IMA
IM model, GTR evolution, HKY substitution model 1 NA GTR simulation using SEQ-GEN based on trees simulated in MS; HKY model specified in IMA
Intralocus recombination, full data set 6 ρ per bp = 0.005, 0.01, 0.02, 0.03, 0.04, 0.05 HKY simulation using SEQ-GEN based on trees simulated in MS; HKY model specified in IMA
Intralocus recombination, nonrecombining blocks 7 ρ per bp = 0, 0.005, 0.01, 0.02, 0.03, 0.04, 0.05 Four-gamete criterion used to identify recombination; HKY simulation using SEQ-GEN based on trees simulated in MS; HKY model specified in IMA
Introgression from third, unsampled species 5 Nefm between first focal species and third species = 0.1, 0.2, 0.3, 0.5, 1.0 5-Ma divergence time between third species and common ancestor of focal species; gene flow only with first focal species
Population structure 5 Nefm among populations within each species = 0.1, 0.2, 0.5, 1.0, 2.0 Four populations of equal size within each species
Linkage among loci 5 r among loci = 0.005, 0.01, 0.02, 0.05, 0.1
Divergent-selective sweep 4 Timing: 1 Ma, 10 kYA Bottlenecks last 100 years; Nef changes are instantaneous; presweep, neutral Nefm = 0.25
Bottleneck size: 1,000, 100
Postsweep Nefm: 0.05, 0.01
IM model, IS evolution, more complex demography 2 NA Population-size change simulated as instantaneous change or exponential growth