Table 1.
NG reaction constants (8) | Reaction constants for NG data in modified one-form model | Reaction constants for KG data in modified one-form model | Reaction constants for averaged data in modified one-form model | |
---|---|---|---|---|
k1 | 111.8 | 1.18×102 | 1.08×102 | 91.8 |
k2 | 48.84 | 54.0 | 59.0 | 82.4 |
k3 | 222.2 | 51.7 | 42.7 | 10.4b |
k4 | 362.0 | 2.24×103 | 57.1 | 38.1b |
k5 | 36.04 | 12.6 | 12.8 | 5.16 |
k6 | 10.74 | 37.9 | 34.7 | 32.3 |
k7 | 8.08 | 1.99×10−6 | 2.56×10−6 | 6.76×10−8b |
k8 | 215.1 | 0.230 | 4.62×10−2 | 5.99×10−3b |
k9 | 0.0369 | 2.17×10−9 | 4.36×10−8 | 3.12×10−8b |
k10 | 0.0185 | 4.39×10−5 | 0.576 | 7.23×10−10b |
j1 | 1.267 | 1.83×10−8 | 48.2 | 33.4 |
j3 | 0.2058 | 1.70×10−5 | 1.45×10−5 | 1.58×10−6b |
j5 | 0.2571 | 1.59×10−2 | 640.2 | 21.8 |
j7 | 7.841 | 0.102 | 3.74×10−8 | 4.46×10−9b |
k3a | 1.677 | 1.44×103 | 49.08 | 151.5 |
k4a | 22.19 | 2.68×102 | 179.2 | 209.9 |
k7a | 17.30 | 1.00 | 5.943 | 4.70 |
k8a | 19.41 | 46.0 | 98.32 | 42.6 |
j3a | 0.3494 | 2.56×103 | 12.90 | 0.185 |
j7a | 0.0022 | 8.30×10−4 | 5.29×10−4 | 2.66×10−5 |
kC1 | 5.432×10−5 | 87.9 | 0.3785 | 2.39×10−6 b |
kC2 | 2.6480 | 5.01 | 2.64×10−8 | 0.031 b |
The units for all association rate constants (k1, k3, k5, k7, k3a, k7a) values are μM−1sec−1. The units for all dissociation rate constants (j1, j3, j5, j7, j3a, j7a) values, turnover rate constants (k2, k4, k6, k8, k4a, k8a, kC1, kC2), and rate constants for ratcheting (k9, k10) are sec−1.
Set equal to zero in the reduced 12 parameter model of the averaged data.
NG: Nesheim group
KG: Krishnaswamy group