Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
a, Control mice: Nkx6.1 is expressed in β-cells. Bars: 20 μm. b, One month post-ablation, 5.05±0.8% of glucagon-expressing cells are Nkx6.1+ (2,855 cells in 277 islets, 5 mice, vs. 0.37±0.3% in controls; 674 α-cells in 39 islets, 3 mice; P=0.035). c, Nkx6.1 expression in glucagon+ cells (top). Some cells also express insulin (middle). YFP+/Insulin+/Nkx6.1+/Glucagon-negative cell (bottom). Bars: 10 μm. d, Proposed reprogramming sequence.
