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. 2010 Jun 1;21(11):1872–1884. doi: 10.1091/mbc.E09-09-0839

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© 2010 by The American Society for Cell Biology

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Figure 6. — H3.3-EGFP preferentially targets transcriptionally active promoters. (A) Percentage of expressed genes with a promoter occupied by indicated combinations of trimethylated (me3) H3K4, H3K9, and H3K27, with or without H3.3. *p < 0.05; **p < 0.001; ns, nonsignificant (Fisher's t test). Percentage of expressed genes among all RefSeq genes included in both Nimblegen and Illumina arrays also is shown (right). (B) Venn diagram analysis of H3.3, DNA methylated, and expressed genes. (C) Venn diagram analysis of H3.3, DNA methylated, and nonexpressed genes. (D) Percentage of H3.3 target HCPs, ICPs, and LCPs as a function of gene expression. **p < 0.001; ns, not significant; chi-square test with Yates' correction.