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. 2010 May 17;7:14. doi: 10.1186/1742-4682-7-14

Figure 9.

Figure 9

Before flare interventions: simulations for patient 491. (A) A larger increase of the corticosteroid dose 4 months before flare would control the inflammation and avoid clinical manifestations of the renal flare; sa = 1.2 A-units/day 4 months before flare (solid curves); sa = 2 A-units/day 4 months before flare (dashed curves). (B) The initial anti-inflammatory therapy would have better results if methods to lower the half-life of the pro-inflammatory mediators, μp, could also be implemented; μp = 0.33/day (solid curves), and μp = 0.66/day (dashed curves). All other parameters are as listed in Table 1 and Table 2.