Table 1.

Endpoints, measuring instruments, and time of data collection

Endpoint of the economic evaluation	Derived from/questionnaire name	Time of measurement (Month)
		Baseline	M 3	M 6	M 9	M 12	M 15
Incidence rate of depression	Depression module of the SCID	X	X				X
Severity of depression	QIDS/Hamilton Scale	X	X			X	X
QALYs	SF-36 EQ-5D	X	X	X	X	X	X
MCI (three-step screening)	Interview of Strawbridge MMSE CDR SKT + MWTB	X					X*
Health sector and patients' costs	Cost questionnaire	X		X		X	X
Laboratory parameters	Safety parameters: ALT, AST, creatinine, TSH	X
	HbA1c	X	X	X	X	X	X
Diabetes-related emotional distress, coping, diabetes self-care activities	PAID SDSCA FKV-15	X	X			X	X
Interpersonal aspects	SE H-Skala K-INK	X	X			X	X

*those patients with a positive MCI screening at baseline