Table 3.
Triglyceride geometric means and 95% confidence intervals (mmol/L) by LPL, APOA5 and APOE genotypes.
LPL-S447X1 | 447SS | 1.15 (1.12-1.19) | APOA5-S19W4 | 19SS | 1.11 (1.07-1.14) |
447SX | 1.02 (0.96-1.07)6 | 19SW | 1.19 (1.10-1.28) | ||
447XX | 0.90 (0.75-1.10) | 19WW | 1.92 (0.94-3.96)9 | ||
LPL-HindIII1 | H+H+ | 1.17 (1.13-1.22) | APOA5- (-1131T/C)5 | -1131TT | 1.11 (1.07-1.14) |
H+H- | 1.07 (1.03-1.11)7 | -1131TC | 1.24 (1.15-1.33) | ||
H-H- | 1.04 (0.97-1.13)8 | -1131CC | 1.39 (0.98-1.95)10 | ||
LPL-D9N2 | 9DD | 1.12 (1.08-1.14) | APOE1 | ε2ε2 | 0.62 (0.35-1.10) |
9DN | 1.25 (1.07-1.47) | ε2 ε3 | 1.19 (1.03-1.29) | ||
9NN | 3.56 | ε3ε3 | 1.08 (1.05-1.12) | ||
LPL-N291S3 | 291NN | 1.12 (1.08-1.14) | ε3ε4 | 1.22 (1.14-1.30)11 | |
291NS | 1.28 (1.11-1.46) | ε4ε4 | 1.50 (1.17-1.92) | ||
291SS | - | ε2ε4 | 1.00 (0.80-1.26) |
Significant differences of ANOVA or the Student t test using log transformed variable (1p < 0.001; 2p = 0.043; 3p = 0.080; 4p = 0.005; 5P = 0.012).
Significant differences (p < 0.05) of post-hoc Bonferroni analysis: 6compared with 447SS; 7,8compared with H+H+; 9compared with 19SS and 19SW; one man TG>11.29 mmol/L; 10compared with -1131TT; 11compared with ε3ε3.