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. 2010 May 27;5(5):e10863. doi: 10.1371/journal.pone.0010863

Figure 3. Induction of anti-PspA5 antibodies in C3H/HePas and C3H/HeJ mice.

Figure 3

C3H/HePas (A) and C3H/HeJ (B and C) were immunized with the different vaccine formulations through the nasal route. Three weeks after the last immunization anti-PspA5 IgG in the sera were detected through ELISA. Concentration of antibodies (mean of 6 animals) is shown. Results are representative of two experiments. Asterisks represent significant differences from control groups or from group immunized with PspA5, when indicated (* P<0.05; ** P<0.005, Mann-Whitney U test).