Figure 1. Transcription profiling of all 11 human cytidine deaminases in cirrhosis.

The A3 transcription data are in the form of box-whisker plots with the mean, quartiles, maxima and minima. Data are normalized to the expression levels of three invariable reference genes (TRIM44, HMBS and LMF2). Asterisks indicate statistically significant up regulation: ** 0.01<p<0.001; * 0.05<p<0.01. Inset) AICDA, APOBEC1 and APOBEC2 transcripts were detected in 0, 1 and 1 HL samples respectively but present in several HBV±HCV samples. APOBEC4 transcripts were undetectable in all samples tested.