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. 2010 May 27;6(5):e1000922. doi: 10.1371/journal.ppat.1000922

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Song et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. The structures of ISBma1, ISBma2, and IS407A and their duplicated target sequences in the B. mallei genomes. IS407A has a pair of two transposase genes, orfA and orfB, while ISBma1 and ISBma2 each contain a single transposase gene. These genes in each type of IS element are flanked by inverted repeats, which are denoted by blue arrows, and then by duplicated insertion target sequences, denoted by yellow arrows. Sequence logo displays [42] of the duplicated insertion target sequences are shown below the corresponding IS element. Solid lines above the Sequence logo display represent the specific regions to which actual target sequences matched, with the most abundant groups at the top. B. Patterns of a disruption of one type of core IS elements by another in B. mallei. Colored solid arrows represent transposases in each IS element. Four types of pattern were found (see Table S1 for details).