Table 2. Repeat sequence pairs associated with the major IS elements in B. mallei.
5′-end | 3′-end | |
IS407A | ||
Inverted Repeatsa | TGACCTGCCCCCT b | AGGGGGCAGGTCA |
Example direct target repeatsc | TGTC | TGTC |
GTAG | GTAG | |
TTCG | TTCG | |
GGGC | GGGC | |
ATCA | ATCA | |
ISBma1 | ||
Inverted Repeats | GGTTCATCGC | GCGATGAACC d |
Example direct target repeats | AATTTTTT | AATTTTTT |
AAAAAAAT | AAAAAAAT | |
AAAAAATA | AAAAAATA | |
CTTTTTTT | CTTTTTTT | |
TTTTTCTT | TTTTTCTT | |
ISBma2 | ||
Inverted Repeats | CAGATTGCTGACAAACCC | GGGTTCGTCAGCAGTCTG |
Example direct target repeats | AGCCAGCTTGCGCTGGCT | AGCCAGCTTGCGCTGGCT |
ACCGCAGCGAAGGCTGCGGT | ACCGCAGCGAAGGCTGCGGT | |
AATGGGCCGGAAACGGCCCATT | AATGGGCCGGAAACGGCCCATT | |
AGGCCCGCCGAAGCGGGCTT | GGGCCGTTTCAAACGGCCCG | |
GGGGCGCTTCGGCGCCCC | GGGGCGCTTCGGCGCCCC |
aInverted repeats are part of the IS elements, that are present on either side of the ends.
bConsensus sequences of the inverted repeats.
cFive examples of the direct repeat target duplicates, which encompass the IS elements. The entire data can be found in Table S3.
dGCGATGA overlaps with the 3′-terminus of the transposase gene in the upstream.