Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 May 27;6(5):e1000970. doi: 10.1371/journal.pgen.1000970

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Boj et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Correlation of mutant/wild-type Log2 gene expression ratios in Hnf4a^pKO versus Hnf1a^+/− islets. (B) Validation of 22 genes using gene-specific qPCR. (C) Heatmap of expression ratios in Hnf4a^pKO and Hnf1a^+/− islets for the 50 most downregulated genes in Hnf4a^pKO islets. (D) Expression of Hnf1a-dependent genes in Hnf4a^pKO islets. Grey dots represent average expression values of genes in Hnf4a^pKO versus control islets. We superimposed red dots to show the subset of genes downregulated in Hnf1a^+/− islets. (E) Expression of Hnf4a-dependent genes in Hnf1a^+/− islets. Grey dots are expression values of all genes, superimposed blue dots are the subset of genes downregulated in Hnf4a ^pKO islets.