Table 1.
Descriptive statistics and ANOVAs for participant and caregiver demographic variables.
| Variables | NC (n = 44) | MCI (n =25) | AD (n = 55) | F | p | |
|---|---|---|---|---|---|---|
| Patient | ||||||
| Age (years) | 68.6 (8.6) | 71.8 (8.4) | 72.9 (9.4) | 2.90 | .059 | |
| Education (years) | 16.1 (2.6) | 15.2 (3.3) | 14.6 (3.4) | 2.49 | .087 | |
| Gender (% Female)1 | 61.4 | 44.0 | 40.0 | 4.70 | .095 | |
| CDR | .11 ( .21) | .58 (.19) | .88 (.47) | 59.28 | .000 | NC<MCI<ADa,b |
| MMSE | 28.9 (1.2) | 26.9 (2.0) | 20.2 (4.1) | 112.36 | .000 | NC>MCI>ADa |
| Logical Memory I | 18.9 (3.0) | 11.0 (5.9) | 5.4 (4.3) | 101.25 | .000 | NC>MCI>ADa |
| Logical Memory II | 18.0 (3.5) | 10.0 (6.4) | 3.5 (4.3) | 101.52 | .000 | NC>MCI>ADa |
| TMT, Part A | 30.4 (18.4) | 41.9 (22.3) | 69.2 (39.6) | 20.80 | .000 | NC<MCI<ADa,c,d |
| TMT, Part B | 73.3 (28.3) | 124.4 (67.3) | 227.8 (82.4) | 62.93 | .000 | NC<MCI<ADa,e |
| Boston Naming | 27.2 (4.6) | 25.7 (3.3) | 22.7 (5.4) | 9.29 | .000 | NC<ADf |
| Animal Fluency | 20.6 (5.2) | 15.0 (3.8) | 11.8 (6.8) | 28.17 | .000 | NC>MCI>ADa,g |
| GDS | 1.91 (2.6) | 3.2 (2.6) | 2.2 (2.6) | 1.95 | .146 | |
| Caregiver/Informant | ||||||
| Age (years) | 61.8 (11.7) | 64.2 (12.5) | 64.1 (11.9) | 0.57 | .569 | |
| Education (years) | 15.9 (2.8) | 15.6 (2.5) | 15.3 (2.7) | 0.57 | .566 | |
| Gender (% Female)1 | 54.5 | 64.0 | 70.9 | 2.80 | .243 | |
1
Chi-square
a
Cohen’s d > 1.0 for significant relationship unless otherwise noted;
b
Cohen’s d = .83 for NC<AD;
c
Cohen’s d = .57 for NC<MCI;
d
Cohen’s d = .85 for MCI<AD;
e
Cohen’s d = .99 for NC<MCI;
f
Cohen’s d = .90 for NC<AD;
g
Cohen’s d = .58 for MC<AD
Note. NC = Normal Controls; MCI = Mild Cognitive Impairment; AD = Alzheimer’s disease; CDR = Clinical Dementia Rating Scale; MMSE = Mini Mental Status Examination, TMT = Trail Making Test