Table 5.
Maximum level of gene reactivation in different cell-types relative to the equivalent value seen in samples injected with ES nuclei (%).
| Relative transcript expressiona |
||||
|---|---|---|---|---|
| Donor cell-typeb | c-Jun | Sox2 | Nanog | Oct4 |
| C2C12 | 516.3 | 0.3 | 2.8 | 2.8 |
| MEF | 130.0 | 3.3 | 0.6 | 0.6 |
| Thymus | 125.6 | 0.9 | 1.0 | 0.7 |
| 10T1/2 | 78.0 | 3.0 | 0.7 | 1.2 |
| ESRA | 230.5 | 78.5 | 85.2 | 108.1 |
| Ratio between mean somatic and ESRA level | 1.1 | 42.1 | 66.6 | 81.1 |
a
Values are shown as % of that for injected ES cell nuclei.
b
Oocytes injected with 250 nuclei and cultured for up to 4 days at 16 °C.