Table 2.
Sham | BDL | |
---|---|---|
Hepatic | ||
5β-Reductase | 9.07 ± 6.91 | 0.85 ± 0.60∗ |
3αHSD | 7.07 ± 3.60 | 0.55 ± 0.34∗∗ |
Cyp7a1 | 2.11 ± 0.81 | 2.33 ± 0.56 |
Adrenal | ||
Cyp11b1 | 8.25 ± 0.74 | 5.74 ± 0.76∗ |
BDL, bile duct ligation; HSD, hydroxysteroid dehydrogenase; Cyp7a1, cholesterol 7a-hydroxylase; Cyp11b1, 11β-hydroxylase.
Hepatic genes corrected for 18S (unchanged between groups). Cyp11b1 is copy no/μgRNA×107.
Mean ± SEM; ∗p <0.05, ∗∗p <0.01.