Table 4.

 Adjusted regression coefficients (95% CI) of toothbrushing on inflammatory markers (n=4830)

	C reactive protein				Fibrinogen
	Mean (SD) mg\l	Age/sex adjusted β*	Fully adjusted† β		Mean (SD) g\l	Age/sex adjusted β	Fully adjusted† β
Twice a day	3.07 (6.41)	Reference	Reference		2.86 (0.70)	Reference	Reference
Once a day	3.51 (6.55)	0.04 (0.02 to 0.06)	0.02 (0.00 to 0.04)		2.95 (0.71)	0.11 (0.06 to 0.15)	0.06 (0.02 to 0.11)
<Once a day	4.18 (6.95)	0.09 (0.06 to 0.13)	0.04 (0.01 to 0.08)		2.98 (0.77)	0.22 (0.12 to 0.32)	0.08 (−0.01 to 0.18)
P value for trend	—	<0.001	0.046		—	<0.001	0.015

*Regression coefficients represent log transformed values.

†Adjusted for age, sex, socioeconomic group, smoking, BMI, family history of cardiovascular disease, hypertension (diagnosed by doctor or clinic blood pressure >140/90 mm Hg), diabetes diagnosed by doctor, visits to dentist, acute infections (including influenza, pneumonia, bronchitis, and upper respiratory tract infections).