Figure 5.

A β1 integrin/caveolin-1/PTEN complex is present in control fibroblasts but cannot be detected in IPF fibroblasts. A: Control fibroblasts were cultured on polymerized collagen. β1 integrin was immunoprecipitated and Western analysis for caveolin-1 or β1 integrin was performed. B: Caveolin-1 was immunoprecipitated and Western analysis for β1 integrin, PTEN, or caveolin-1 was performed. Immunoprecipitation using IgG antibody is shown as a control. C: IPF fibroblasts were cultured on polymerized collagen. β1 integrin was immunoprecipitated and Western analysis for caveolin-1 or β1 integrin was performed. Note: Immunoprecipitation using IgG antibody is shown as a control.